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Regulation of acetohydroxy acid synthase activities inEscherichia coliK-12 by small metabolites

Authors
Journal
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
0167-4781
Publisher
Elsevier
Publication Date
Volume
866
Issue
1
Identifiers
DOI: 10.1016/0167-4781(86)90094-1
Keywords
  • Cyclic Amp
  • Indole Acetic Acid
  • Acetohydroxy Acid Synthase
  • Gene Expression
  • (E. Coli)

Abstract

Abstract The effects of several metabolites (indole acetic acid, imidazole acetic acid and indole) on acetohydroxy acid synthase activities have been examined in both cya + and cya − strains. Specifically, indole acetic acid caused an increase in the rate of acetohydroxy acid synthase synthesis under both in vivo and in vitro conditions. Taken together, these data suggest that small metabolites, other than cAMP, can alter acetohydroxy acid synthase gene expression.

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