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Transtubular bioreactor: A perfusion device for mammalian cell cultivation

Authors
Journal
Biotechnology Techniques
0951-208X
Publisher
Springer-Verlag
Publication Date

Abstract

A transtubular mammalian cell perfusion chamber has been developed that allows separate delivery and control of medium and gas flow to the cells. The hydrodynamic and mass transfer characteristics of the reactor are studied experimentally for both gas and liquid components. Feasibility and potential of the transtubular reactor are demonstrated by the growth of a hybridoma cell line.

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