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Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT

Authors
Journal
Trends in Immunology
1471-4906
Publisher
Elsevier
Publication Date
Volume
28
Issue
8
Identifiers
DOI: 10.1016/j.it.2007.06.006

Abstract

A general theme in gene regulation is that transcription factors never function alone. Recent studies have emphasized this concept for regulatory T cells, a unique lineage of CD4 + T cells that exert active immune suppression and are essential to maintaining self-tolerance.

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