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A new diterpene from the stems ofTrigonostemon heterophyllus

Authors
Journal
Chinese Journal of Natural Medicines
1875-5364
Publisher
Elsevier
Volume
12
Issue
4
Identifiers
DOI: 10.1016/s1875-5364(14)60058-3
Keywords
  • Trigonostemon Heterophyllus
  • Trigonoheterene B
  • Diterpene
  • Antibacterial Activities
Disciplines
  • Chemistry

Abstract

Abstract Aim To investigate the chemical constituents in the stems of Trigonostemon heterophyllus. Method The chemical constituents were isolated by column chromatography on silica gel, Rp-18, and Sephadex LH-20, and their structures were elucidated on the basis of spectroscopic analysis. Results Three compounds were isolated and identified as a new diterpene, trigonoheterene B (1), together with two known compounds, trigonostemone (2) and trigonochinene B (3). Conclusion Compound 1 is new. Compounds 2 and 3 showed antibacterial activities.

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