Affordable Access

Publisher Website

Liponucleoside thin films: The special behaviour of guanosine

Authors
Journal
Colloids and Surfaces B Biointerfaces
0927-7765
Publisher
Elsevier
Publication Date
Volume
103
Identifiers
DOI: 10.1016/j.colsurfb.2012.10.019
Keywords
  • Nucleolipids
  • Surface-Assembly
  • Langmuir Films
  • Langmuir–Blodgett Films

Abstract

Abstract We performed a comparative study of self-assembling properties of liponucleoside materials containing different nucleobases in their hydrophilic headgroups, but possessing the same type of lipophilic moiety in their hydrophobic tails. Surface pressure versus area isotherms (π(A)) of monolayers formed at the air–water interface show that guanine-based materials form stable monolayer films exhibiting a profound first order phase transition from the liquid expanded to the condensed phase. Materials based on other nucleobases form less stable films exhibiting a liquid-like behaviour. Analysis of surface structures of Langmuir films with Brewster angle microscopy (BAM) and of Langmuir–Blodgett (LB) films deposited on mica surface by atomic force microscopy (AFM) confirms surface organization as resolved from the isotherms. The specific behaviour of molecules with a guanine head group is attributed to their optimal hydrophilic/hydrophobic balance, which is associated with the low water solubility of guanine derivatives.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Elastic behaviour of TiN thin films

on Thin Solid Films Jan 01, 1993

Two-dimensional behaviour of very thin4He films on...

on Physica B Condensed Matter Jan 01, 1995
More articles like this..