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Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats.

Authors
  • 1
Type
Published Article
Journal
BMC Cancer
1471-2407
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
9
Pages
259–259
Identifiers
DOI: 10.1186/1471-2407-9-259
PMID: 19640308
Source
Medline

Abstract

Overall, these observations suggest that the predominant effect of auraptene was to delay the development of tumors possibly through the suppression of cyclin D1 expression. These results point to the potential chemopreventive effects of auraptene in mammary carcinogenesis.

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