Publisher Summary This chapter presents guidelines that provide some guidance in selecting a safety relief valve (SRV) for use in a specific application or process condition where the use of traditional spring-operated valves could be questionable. The solution should entail the most economical and safe, reliable, long-term operation. Some manufacturers can offer full-bore POSRVs where a larger orifice can be obtained in a smaller size valve by increasing the curtain area. Many SRVs are installed close to reciprocating compressors. Reciprocating compressors can generate high-frequency pressure peaks and can be very destructive for downstream equipment. An important factor in selecting the correct SRV is choosing the correct materials for the application.