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Directed Reduction of β-Amino Ketones to Syn or Anti 1,3-Amino Alcohol Derivatives

Authors
Journal
Organic Letters
1523-7060
Publisher
American Chemical Society
Publication Date
Keywords
  • Article

Abstract

The reduction of β-amino ketones with samarium(II) iodide has been investigated. Either the syn or anti 1,3-amino alcohols can be obtained as the major product due to a divergence in selectivity with different N-protecting groups.

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