Affordable Access

Publisher Website

Genetics of human prefrontal function

Authors
Journal
Brain Research Reviews
0165-0173
Publisher
Elsevier
Publication Date
Volume
43
Issue
1
Identifiers
DOI: 10.1016/s0165-0173(03)00205-4
Keywords
  • Genetics
  • Comt
  • Intelligence
  • Prefrontal Function
  • Endophenotype
Disciplines
  • Biology
  • Medicine
  • Psychology

Abstract

Abstract Evolution of the prefrontal cortex was an essential precursor to civilization. During the past decade, it became increasingly obvious that human prefrontal function is under substantial genetic control. In particular, heritability studies of frontal lobe-related neuropsychological function, electrophysiology and neuroimaging have greatly improved our insight. Moreover, the first genes that are relevant for prefrontal function such as catechol- O-methyltransferase (COMT) are currently discovered. In this review, we summarize the present knowledge on the genetics of human prefrontal function. For historical reasons, we discuss the genetics of prefrontal function within the broader concept of general cognitive ability (intelligence). Special emphasis is also given to methodological concerns that need to be addressed when conducting research on the genetics of prefrontal function in humans.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Genetics of human prefrontal function.

on Brain research. Brain research... September 2003

On some functions of the human prefrontal cortex.

on Annals of the New York Academy... Dec 15, 1995

Functions of the prefrontal cortex in the human br...

on Journal of Korean Medical Scie... Dec 01, 1998

Functions of the prefrontal cortex in the human br...

on Journal of Korean medical scie... December 1998
More articles like this..