Affordable Access

Publisher Website

The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase—GW311616A a development candidate

Authors
Publisher
Elsevier Ltd
Publication Date
Volume
11
Issue
7
Identifiers
DOI: 10.1016/s0960-894x(01)00078-6
Disciplines
  • Pharmacology

Abstract

Abstract The discovery of a potent intracellular inhibitor of human neutrophil elastase which is orally active and has a long duration of action is described. The pharmacodynamic and pharmacokinetic properties of a trans-lactam development candidate, GW311616A, are described.

There are no comments yet on this publication. Be the first to share your thoughts.