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Synthesis of Pyridyl and Quinolyl Substituted 2-Aminothiazoles.

McGill University
Publication Date
  • Chemistry.


In the first stage of the present investigation, the 2-amino-4-(x-pyridyl)-thiazole and 2-amino-4-(y-quinolyl)- thiazoles were synthesized. Various methods were investigated. The best method, giving the highest yields and the purest product, was found to be that in which the appropriate acetylpyridine and acetylquinoline hydrobromides were condensed with thiourea in polar solvents.

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