Affordable Access

Publisher Website

Chiral phosphine oxides and chiral esters in stereoselective intermolecular acylation reactions of phosphine oxides

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
37
Issue
41
Identifiers
DOI: 10.1016/0040-4039(96)01612-7

Abstract

Abstract Single diastereomers of β-keto phosphine oxides have been generated from intermolecular acylation of phosphine oxides using either chiral esters or chiral phoshine oxides. In most cases, reduction of the ketone products was not affected by the presence of extra chiral centres. Some mechanistic points of interest in the acylation reactions are discussed.

There are no comments yet on this publication. Be the first to share your thoughts.