Abstract The ideal gas has been reinvestigated in the framework of Tsallis nonextensive statistics, which can be called nonextensive gas. According to the modified thermodynamic relationships, and applying the nonextensive gas model to analyze actual gas, the relationship between the nonextensive parameter and the second virial coefficient can be deduced. On the other hand, this coefficient can also be expressed as the integration of interaction potential between the molecules of actual gas. This indicates that the nonextensive parameter may be related to the interaction potential. Our further analysis to the relation seems to imply that the nonextensive parameter is irrelevant to the thermodynamic temperature of the gas.