Affordable Access

deepdyve-link
Publisher Website

3D hyperpolarized C-13 EPI with calibrationless parallel imaging.

Authors
  • Gordon, Jeremy W1
  • Hansen, Rie B2
  • Shin, Peter J3
  • Feng, Yesu3
  • Vigneron, Daniel B3
  • Larson, Peder E Z3
  • 1 Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States. Electronic address: [email protected] , (United States)
  • 2 Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark. , (Denmark)
  • 3 Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States. , (United States)
Type
Published Article
Journal
Journal of Magnetic Resonance
Publisher
Elsevier
Publication Date
Apr 01, 2018
Volume
289
Pages
92–99
Identifiers
DOI: 10.1016/j.jmr.2018.02.011
PMID: 29476930
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

With the translation of metabolic MRI with hyperpolarized 13C agents into the clinic, imaging approaches will require large volumetric FOVs to support clinical applications. Parallel imaging techniques will be crucial to increasing volumetric scan coverage while minimizing RF requirements and temporal resolution. Calibrationless parallel imaging approaches are well-suited for this application because they eliminate the need to acquire coil profile maps or auto-calibration data. In this work, we explored the utility of a calibrationless parallel imaging method (SAKE) and corresponding sampling strategies to accelerate and undersample hyperpolarized 13C data using 3D blipped EPI acquisitions and multichannel receive coils, and demonstrated its application in a human study of [1-13C]pyruvate metabolism. Copyright © 2018 Elsevier Inc. All rights reserved.

Report this publication

Statistics

Seen <100 times