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Effect of radiotherapy on γ-glutamyl transpeptidase and lactic dehydrogenase activity in cancer of the uterine cervix

Authors
Journal
Clinica Chimica Acta
0009-8981
Publisher
Elsevier
Publication Date
Volume
37
Identifiers
DOI: 10.1016/0009-8981(72)90434-2
Disciplines
  • Medicine

Abstract

Abstract In 86 women with squamo-epithelial cancer of the uterine cervix the γ-glutamyl transpeptidase and lactic dehydrogenase activity was determined prior to radiotherapy, immediately after radiotherapy and 7 days after its termination. A statistically significant increase in γ-glutamyl transpeptidase activity of serum was established after a therapeutic doses of radium γ rays. On the other hand, the behaviour of lactic dehydrogenase was virtually unaffected. The results obtained point to γ-glutamyl transpeptidase determination as an early criterion in evaluating the effect of radiotherapy.

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