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Treatment of patients with hepatitis C virus on the waiting list

Authors
Journal
Liver Transplantation
1527-6465
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
9
Issue
11
Identifiers
DOI: 10.1053/jlts.2003.50247
Disciplines
  • Biology
  • Medicine

Abstract

Key Points 1. Over 90% of patients with hepatitis C on the waiting list might be candidates for therapy with interferon plus ribavirin. 2. One must exercise caution in the treatment of these patients. Those with Child-Turcotte-Pugh score >11 or Model for End-Stage Liver Disease score >25 should be excluded from treatment. 3. Sustained virologic response (hepatitis C virus RNA-negative is mainly dependent on viral genotype, with 50% of genotype 2 and 3 patients achieving sustained virologic response. 4. The ability to achieve sustained virologic response in genotype 1 patients is dependent on dose and duration of treatment. 5. Patients rendered hepatitis C virus RNA-negative pre-transplantation may not experience posttransplantation recurrence.

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