Affordable Access

Publisher Website

Small heat shock protein expression and functions during development

Authors
Journal
The International Journal of Biochemistry & Cell Biology
1357-2725
Publisher
Elsevier
Volume
44
Issue
10
Identifiers
DOI: 10.1016/j.biocel.2012.03.009
Keywords
  • Small Heat Shock Proteins
  • Development
  • Diapause
  • Differentiation
  • Apoptosis
Disciplines
  • Biology
  • Medicine

Abstract

Abstract The expression of small heat shock proteins is tightly regulated during development in multiple organisms. As housekeeping proteins, small heat shock proteins help protect cells from apoptosis, stabilize the cytoskeleton and contribute to proteostasis. Consistently, depletion of one small heat shock protein is usually not detrimental due to a certain level of redundancy between the functions of each small heat shock protein. However, while their stress-induced expression is regulated by heat shock factors, their constitutive expression is under the control of other specific transcription factors, suggesting the existence of very specialized functions. This review focuses on the expression patterns and functions of small heat shock proteins in various organisms during development. This article is part of a Directed Issue entitled: Small HSPs in physiology and pathology.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Expression and function of small heat shock protei...

on Seminars in Cell and Developme... October 2003

Expression of heat shock factor and heat shock pro...

on Plant molecular biology November 1995

Heat shock protein gene expression during Xenopus...

on Cellular and Molecular Life Sc... January 1997

Expression of heat shock proteins during developme...

on Plant molecular biology October 1993
More articles like this..