Affordable Access

Surface-Enhanced Raman Spectroscopy Based Quantitative Bioassay on Aptamer-Functionalized Nanopillars Using Large-Area Raman Mapping

Authors
Publisher
American Chemical Society
Publication Date
Keywords
  • Surface-Enhanced Raman Spectroscopy (Sers) Has Been Used In A Variety Of Biological Applications Due
  • Here
  • We Report A Sers-Based Biosensing Approach For Quantitative Detection Of Biomolecules
  • A Sers Substrate Bearing Gold-Decorated Silicon Nanopillars Is Functionalized With Aptamers For Sens
  • In This Study
  • Tamra-Labeled Vasopressin Molecules In The Picomolar Regime (1 Pm To 1 Nm) Are Specifically Captured
  • From The Experimental Results
  • We Show Concentration-Dependent Sers Responses In The Picomolar Range By Integrating Sers Signal Int
  • It Is Also Noted That Our Signal Mapping Approach Significantly Improves Statistical Reproducibility
  • Furthermore
  • We Have Developed An Analytical Model Capable Of Predicting Experimental Intensity Distributions On
  • Lastly
  • We Have Calculated The Minimum Needed Area Of Raman Mapping For Efficient And Reliable Analysis Of E
  • Combining Our Sers Mapping Analysis With An Aptamer-Functionalized Nanopillar Substrate Is Found To

Abstract

Surface-Enhanced Raman Spectroscopy Based Quantitative Bioassay on Aptamer-Functionalized Nanopillars Using Large-Area Raman Mapping - DTU Orbit (25/04/14) Surface-Enhanced Raman Spectroscopy Based Quantitative Bioassay on Aptamer- Functionalized Nanopillars Using Large-Area Raman Mapping - DTU Orbit (25/04/14) Yang, Jaeyoung; Palla, Mirko; Bosco, Filippo; Rindzevicius, Tomas; Alstrøm, Tommy Sonne; Schmidt, Michael Stenbæk; Boisen, Anja; Ju, Jingyue; Lin, Qiao / Surface-Enhanced Raman Spectroscopy Based Quantitative Bioassay on Aptamer- Functionalized Nanopillars Using Large-Area Raman Mapping. In: ACS Nano, Vol. 7, No. 6, 2013, p. 205350-5359. Publication: Research - peer-review › Journal article – Annual report year: 2013

There are no comments yet on this publication. Be the first to share your thoughts.