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Symptoms of chronic rhinosinusitis with and without nasal polyps

Authors
Journal
Clinical and Translational Allergy
2045-7022
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
3
Identifiers
DOI: 10.1186/2045-7022-3-s2-o2
Keywords
  • Oral Presentation
Disciplines
  • Biology
  • Medicine

Abstract

Symptoms of chronic rhinosinusitis with and without nasal polyps ORAL PRESENTATION Open Access Symptoms of chronic rhinosinusitis with and without nasal polyps Dirk Dietz de Loos1*, Claire Hopkins2, Wytske Fokkens1 From 9th Symposium of Experimental Rhinology and Immunology of the Nose (SERIN 2013) Leuven, Belgium. 21-23 March 2013 Background According to EPOS, chronic rhinosinusitis with and without nasal polyps diagnoses are defined by clinical cri- teria, supported with endoscopy. We want to know if it is possible to make an accurate distinction between patients with and without nasal polyps based on a limited number of clinical criteria, collected by health-related quality of life questionnaires. A validated instrument that can dif- ferentiate patients with chronic rhinosinusitis with and without nasal polyps could be used in epidemiologic research. Methods We collected RSOM-31 (Rhinosinusitis Outcome Mea- surement) questionnaires from CRS patients with and without nasal polyps and compared mean total RSOM- 31 scores, mean domain scores, mean symptoms scores, and percentages of patients reporting symptoms per diagnosis based on endoscopy and CT scan. Further- more a prediction model was obtained by multivariable regression analysis, to define individual risk for nasal polyps in daily practice. Results RSOM-31 Questionnaires were collected from 234 patients. Although total RSOM-31 score was similar and symptomatology considerably overlapping, patients with CRSwNP (with nasal polyps) scored significantly higher and more often on nasal symptoms as ‘Rhinorrhoea’ and ‘Decreased sense of taste or smell’. Patients with CRSsNP (without nasal polyps) significantly scored more often and higher on ‘facial pain’ and ‘ear pain’. A prediction model containing patient characteristics and the RSOM-31 items ‘Rhinorrhoea’, ‘Decreased sense of taste or smell’, ‘facial pain’, ‘ear pain’ and ‘Inconvenience of always having to carry tissues around’ gives a sensitivity of 81% and specifi- cit

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