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The release of oxytocin from spinal cord synaptosomes by high KCL depolarizing stimulus: A calcium dependent process

Authors
Journal
Life Sciences
0024-3205
Publisher
Elsevier
Publication Date
Volume
54
Issue
14
Identifiers
DOI: 10.1016/0024-3205(94)00495-1

Abstract

Abstract Oxytocin (OT) release from synaptosomes isolated from the thoracic (T) and lumbosacral (LS) regions of the spinal cord was evoked by 56 mM potassium chloride (KCl). The release mechanism was shown to be a calcium dependent process. The ability of high KCl to evoke OT release from isolated nerve terminals in a calcium dependent manner provides additional support for the role of OT as a neurotransmitter in the spinal cord.

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