Affordable Access

Publisher Website

Regioselective double disulfide formation using silylchloride-sulfoxide system

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
33
Issue
8
Identifiers
DOI: 10.1016/s0040-4039(00)91864-1
Keywords
  • Peptide
  • Disulfide Bond
  • Silylchloride-Sulfoxide
  • Conotoxin M1
  • β-Hanp

Abstract

Abstract Two intermolecular or intramolecular disulfide bonds are formed regioselectively by the combination of silylchloride-sulfoxide method with conventional oxidation method. This stepwise method for double disulfide formation is successfully applied to the syntheses of conotoxin M1 and β-human atrial natriuretic peptide.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Synthesis of human endothelin-1 by regioselective...

on Tetrahedron Letters Jan 01, 1995

Disulfide bond-forming reaction using a dimethyl s...

on International journal of pepti... April 1995

[A novel synthetic approach of tryptophan-containi...

on Yakugaku zasshi : Journal of t... February 2000

Synthesis of the IGF-II-like hormone vesiculin usi...

on Organic & Biomolecular Chemist... May 21, 2013
More articles like this..