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Newborn primary congenital glaucoma: Histopathologic features of the anterior chamber filtration angle

Authors
Journal
Journal of American Association for Pediatric Ophthalmology and Strabismus
1091-8531
Publisher
Elsevier
Volume
16
Issue
6
Identifiers
DOI: 10.1016/j.jaapos.2012.06.012
Disciplines
  • Biology
  • Medicine

Abstract

We present histopathologic findings that have not been previously reported as associated with abnormalities of the anterior chamber angle underlying newborn primary congenital glaucoma as a distinct entity. The major histopathologic findings were partial absence and retrodisplacement of Schlemm's canal, hypoplasia of the trabecular meshwork, broad attachment of ciliary muscle to the meshwork, and anterior insertion of hypoplastic iris with the formation of a pseudomembrane. These profound anatomic derangements explain why goniosurgery is frequently unsuccessful in cases of newborn glaucoma.

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