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Triphosgene, an efficient acid activator for the Staudinger reaction

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
41
Issue
3
Identifiers
DOI: 10.1016/s0040-4039(99)02074-2
Keywords
  • Triphosgene
  • Staudinger Reaction
  • Azetidinones
  • Ketenes
  • Imines

Abstract

Abstract An efficient one-step synthesis of β-lactams by the reaction of imines with acids in the presence of triphosgene and triethylamine has been described.

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