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Electrophoretic profile of serum proteins in opium and heroin dependents.

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Publication Date
Keywords
  • Rm Therapeutics. Pharmacology
  • Rs Pharmacy And Materia Medica
Disciplines
  • Biology
  • Medicine

Abstract

þÿ Kerman University of Medical Sciences, Kerman, Iran. http://www.kmu.ac.ir Am J Drug Alcohol Abuse. ٢٠٠٨;٣٤(٦):٧٦٩-٧٣. Electrophoretic profile of serum proteins in opium and heroin dependents. Divsalar K, Meymandi MS, Saravani R, Zarandi MM, Shaikh-Al-Eslami A. Source Kerman Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran. Abstract OBJECTIVES: In this cross-sectional case-control study, albumin and globulin profile in the serum of opium and heroine addicts have been compared with correspondent values in a matched control group. METHODS: Opioid consumption was confirmed by laboratory diagnostic tests on urine samples and protein electrophoresis of serum was performed to determine the concentration and profile of serum proteins. RESULTS: There was no significant difference in albumin, alpha(١)-globulin, alpha(٢)-globulin, and beta-globulin concentration among groups. Gamma-globulin concentration in opium and heroin addicts showed no significant difference, but it was significantly lower in comparison to the control group. CONCLUSION: This finding may be attributed to the higher probability of infectious diseases in opioids addicts. PMID: ١٩٠١٦١٨٢ [PubMed - indexed for MEDLINE]

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