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Functions of baseplate components in bacteriophage T4 infection: II. Products of genes 5, 6, 7, 8, and 10

Authors
Journal
Virology
0042-6822
Publisher
Elsevier
Publication Date
Volume
55
Issue
2
Identifiers
DOI: 10.1016/0042-6822(73)90179-7

Abstract

Abstract Thermolabile mutants in genes 5, 6, 7, 8, and 10 of phage T4D, which are inactivated more rapidly than wild type at high temperatures, have been used to examine the functions of these gene products in phage adsorption. Comparison of the thermolabilities of whole phage and urea treated particles, the yield of active urea treated phage from heat inactivated phage particles, and the infectivity of heated particles on spheroplasts enabled us to determine that P10 functions only at an early stage of infection whereas P5, P6, P7, and P8 are involved at later stages.

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