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The 3-dimensional cellular automata for HIV infection

Authors
Journal
Physica A Statistical Mechanics and its Applications
0378-4371
Publisher
Elsevier
Publication Date
Volume
399
Identifiers
DOI: 10.1016/j.physa.2013.12.018
Keywords
  • Aids
  • Hiv
  • 3-D Cellular Automata
Disciplines
  • Medicine

Abstract

Abstract The HIV infection dynamics is discussed in detail with a 3-dimensional cellular automata model in this paper. The model can reproduce the three-phase development, i.e., the acute period, the asymptotic period and the AIDS period, observed in the HIV-infected patients in a clinic. We show that the 3D HIV model performs a better robustness on the model parameters than the 2D cellular automata. Furthermore, we reveal that the occurrence of a perpetual source to successively generate infectious waves to spread to the whole system drives the model from the asymptotic state to the AIDS state.

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