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Echinoclasterol sulfate phenethylammonium salt, a unique steroid sulfate from the marine sponge,Echinoclathria subhispida

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
34
Issue
36
Identifiers
DOI: 10.1016/s0040-4039(00)73846-9

Abstract

Abstract A phenethylammonium salt of a new steroid sulfate, echinoclasterol sulfate ( 1) has been isolated from the marine sponge, Echinoclathria subhispida. The structure was determined by interpretation of spectral data including 2D NMR and FABMS. It exhibited antifungal activity against Mortierella ramannianus, and cytotoxicity against PC-9 human lung cancer cells.

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