Affordable Access

Therapeutic options in advanced cutaneous T cell lymphomas: A role for interferon alfa-2a (Roferon®-A)

Authors
Journal
Seminars in Oncology
0093-7754
Publisher
Elsevier - WB Saunders
Publication Date
Disciplines
  • Medicine

Abstract

Abstract Interferon alfa-2a (Roferon ®-A) was given to 20 patients with advanced cutaneous T cell lymphomas, all of whom were heavily pretreated. Objective responses were seen in nine of the 20 patients, including seven partial and two complete responses. The median response duration was 5.5 months, with three of the responses lasting 2 or more years. Toxicity was moderate but was alleviated by dose reductions. These results demonstrate that Roferon ®-A is highly effective in the treatment of advanced refractory cutaneous T cell lymphomas. The role of this treatment in earlier stages of disease and in combination with other standard forms of therapy needs to be evaluated.

There are no comments yet on this publication. Be the first to share your thoughts.