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2-Year Outcomes of High Bleeding Risk Patients After Polymer-Free Drug-Coated Stents.

  • Garot, Philippe1
  • Morice, Marie-Claude2
  • Tresukosol, Damras3
  • Pocock, Stuart J4
  • Meredith, Ian T5
  • Abizaid, Alexandre6
  • Carrié, Didier7
  • Naber, Christoph8
  • Iñiguez, Andres9
  • Talwar, Suneel10
  • Menown, Ian B A11
  • Christiansen, Evald H12
  • Gregson, John4
  • Copt, Samuel13
  • Hovasse, Thomas2
  • Lurz, Philipp14
  • Maillard, Luc15
  • Krackhardt, Florian16
  • Ong, Paul17
  • Byrne, Jonathan18
  • And 5 more
  • 1 Hôpital Claude Galien, Institut Cardiovasculaire Paris-sud Ramsay-Générale de Santé, Quincy Sous-Sénart, France; Hôpital Privé Jacques Cartier, Institut Cardiovasculaire Paris-sud Ramsay-Générale de Santé, Massy, France. , (France)
  • 2 Hôpital Privé Jacques Cartier, Institut Cardiovasculaire Paris-sud Ramsay-Générale de Santé, Massy, France. , (France)
  • 3 Siriraj Hospital, Bangkok, Thailand. , (Thailand)
  • 4 London School of Hygiene and Tropical Medicine, London, United Kingdom. , (United Kingdom)
  • 5 MonashHeart and Monash University, Melbourne, Australia. , (Australia)
  • 6 Instituto Dante Pazzanese de Cardiologia, São Paulo, Brazil, and Hospital Albert Einstein, São Paulo, Brazil. , (Brazil)
  • 7 Cardiology Department, Toulouse Rangueil Hospital, Toulouse, France. , (France)
  • 8 Department of Medical Statistics, Contilia Heart and Vascular Centre, Elisabeth Krankenhaus, Essen, Germany. , (Germany)
  • 9 Cardiology Department, Complejo Hospitalario Universitario de Vigo, Hospital Meixoeiro, Meixoeiro, Spain. , (Spain)
  • 10 Dorset Heart Centre, Royal Bournemouth Hospital, Bournemouth, United Kingdom. , (United Kingdom)
  • 11 Department of Cardiology, Craigavon Cardiac Center, Portadown, United Kingdom. , (United Kingdom)
  • 12 Department of Cardiology, Aarhus University Hospital, Skejby, Denmark. , (Denmark)
  • 13 Biosensors Europe, Morges, Switzerland. , (Switzerland)
  • 14 Department of Internal Medicine/Cardiology, Universität Leipzig-Herzzentrum, Leipzig, Germany. , (Germany)
  • 15 Service de Cardiologie, Groupement de Coopération Sanitaire Etablissements de Santé, Axium-Rambot, City, France. , (France)
  • 16 Department of Cardiology, Charité Campus Virchow Klinikum, Berlin, Germany. , (Germany)
  • 17 Tan Tock Seng Hospital, Singapore. , (Singapore)
  • 18 Department of Cardiology, King's College Hospital, London, United Kingdom. , (United Kingdom)
  • 19 St. Thomas Hospital, London, United Kingdom. , (United Kingdom)
  • 20 Cardiovascular European Research Center, Massy, France. , (France)
  • 21 Cardiovascular Department, Hôpital de la Tour, Geneva, Switzerland. Electronic address: [email protected] , (Switzerland)
Published Article
Journal of the American College of Cardiology
Publication Date
Jan 17, 2017
DOI: 10.1016/j.jacc.2016.10.009
PMID: 27806919


Safety and efficacy benefits of DCS over BMS were maintained for 2 years in high bleeding risk patients. Rates of major bleeding and coronary thrombotic events were no different and were associated with a substantial and comparable mortality risk. (A Prospective Randomized Comparison of the BioFreedom Biolimus A9 Drug Coated Stent Versus the Gazelle Bare Metal Stent in Patients With High Risk of Bleeding [LEADERS FREE]; NCT01623180).

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