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N-Mononitrosopyridinol carbamate: The principal mutagen formed by nitrosation of pyridinol carbamate

Authors
Journal
Cancer Letters
0304-3835
Publisher
Elsevier
Publication Date
Volume
18
Issue
2
Identifiers
DOI: 10.1016/0304-3835(83)90060-5

Abstract

Abstract The principal mutagen formed by the reaction of equimolar amounts of pyridinol carbamate and nitrite was isolated, and identified as N-mononitrosopyridinol carbamate on the basis of its spectroscopic data. By microbial mutagenesis assay, the nitroso compound was proved to be a potent directacting mutagen towards base-pair substitution strains.

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