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Über die strahlensensibilisierende wirkung des 5-bromuracils

Authors
Journal
Journal of Molecular Biology
0022-2836
Publisher
Elsevier
Publication Date
Volume
3
Issue
6
Identifiers
DOI: 10.1016/s0022-2836(61)80085-5

Abstract

5-Bromouracil and 5-bromodeoxyuridine are hardly altered by u.v.-irradiation (in water or in ice). On the other hand 5-bromouracil, which is incorporated in deoxyribonucleic acid, is dehalogenated to a great extent. The amount of thymine dimer formed in bacterial DNA by u.v.-irradiation decreases after incorporation of 5-bromouracil.

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