Abstract Detailed bathymetric and magnetic data, complemented by nine dredge stations, define the eastern and western limits of a belt of high-amplitude magnetic anomalies associated with the Galapagos hot spot. The hypothesis of “magnetic telechemistry” was tested and locally confirmed. High amplitudes correspond to high remanence, susceptibility, FeO T, TiO 2, and presumably titanomagnetite concentration. The average remanence of surface samples in the high-amplitude zone is 0.027 emu/cm 3 (range, 0.009–0.085 emu/cm 3), about 4 times that of the normal-amplitude zone. Magnetic amplitudes are only 2–2.5 times higher, however. If the greater TiO 2/FeO T ratio of high-amplitude zone basalts also characterizes the titanomagnetites, remanence in the high-amplitude zone may fall off more rapidly with depth in the crust as a result of reheating. Alternatively, small pillows of high remanence are more common than larger pillows at the top of the high-amplitude zone crust; FeTi basalt may also be concentrated in the upper part of the crust. Anomaly amplitudes are highest at the ends of the zone, particularly in the east. As asthenosphere crystal slushes presumably flow away from the Galapagos plume, progressive crystal fractionation may enrich residual magmas in FeO T and TiO 2. The Galapagos FeTi zone terminates abruptly against transform fractures at both ends, perhaps because subaxial flow is dammed at the transforms. The FeTi-producing crystal slushes have advanced east and west at speeds up to 10 cm/yr since they first appeared at the spreading axis at least 6.6 m.y. B.P. Their progressive advance was connected with the progressive southward jumps of the spreading axis east of the Galapagos hot spot, and northward jumps to the west.