Publisher Summary This chapter reviews the research that has explored variables that can shape employment outcomes for people with an intellectual disability. The chapter focuses on determining employee success as measured by employer satisfaction and attempts to anchor this against satisfaction with employees without disabilities. The chapter provides an overview of the literature and research of immediate relevance at the macrosystem level, including changes in how “disability” has been understood in relation to the broader ecological context, and the prevailing belief system and culture in which employment, intellectual disability, and other forms of disability are embedded. The chapter focuses on research more directly predictive of successful employment outcomes of people with an intellectual disability, multiple disabilities, and other forms of disability. The chapter discusses the future directions for maximizing successful employment outcomes of people with an intellectual disability.