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Some in vivo effects in the rat induced by chlorprothixene and potassium oxonate

Authors
Journal
Pharmacological Research Communications
0031-6989
Publisher
Elsevier
Publication Date
Volume
7
Issue
2
Identifiers
DOI: 10.1016/s0031-6989(75)80015-4
Keywords
  • Metabolism And Biochemical Pharmacology

Abstract

Summary Chlorprothixene treatment in the rat prolonged bleeding time, inhibited collagen-induced aggregation of blood platelets and in the presence of potassium oxonate caused an elevation in serum urate levels. A red discharge which appeared around the eyes fluoresced under exposure to U.V. light and possessed an absorption spectra characteristic of porphyrins.

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