Affordable Access

Publisher Website

(pro)renin receptor: A stable molecule

Authors
Journal
Journal of Natural Science Biology and Medicine
0976-9668
Publisher
Medknow Publications
Publication Date
Volume
2
Issue
2
Identifiers
DOI: 10.4103/0976-9668.92321
Keywords
  • Original Article
Disciplines
  • Biology

Abstract

Background: Basically, (pro)renin acts via a specific receptor, (pro)renin receptor (PRR) binding between renin and prorenin, its inactive proenzyme form. The study on the molecular level of PRR can give useful knowledge to help understand many renal disorders. Method: Here, the author focuses on the stability of the PRR molecule. The mutation prone positions within the PRR molecule was assessed using standard reference technique. Result: The study showed there is no identified mutation prone position within the PRR molecule. Conclusion: This imply the high stability of PRR. This means that PRR rarely undergoes mutation. The reported mutation in PRR should be a very rare episode and the study on the specific cause is warranted.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Renin, (pro)renin and receptor: an update.

on Clinical Science March 2011

The (pro)renin receptors.

on Journal of Molecular Medicine June 2008

[(Pro) renin receptor].

on Nihon yakurigaku zasshi. Folia... August 2008

[(Pro) renin receptor].

on Nihon rinsho. Japanese journal... April 2009
More articles like this..