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Paraplacental passage of3H-prostaglandin F2

Authors
Journal
Prostaglandins & Other Lipid Mediators
0090-6980
Publisher
Elsevier
Publication Date
Volume
23
Issue
2
Identifiers
DOI: 10.1016/0090-6980(82)90048-x
Disciplines
  • Medicine

Abstract

Abstract Prostaglandins F 2α permeates the live and denaturated whole fetal membranes as well as their isolated components chorion and amnion. The permeability constant in our vitro method is 1.3 × 10 −3 cm/min for PG. If 40 mg PG are instilled intra-amniotically at term — as used in therapeutical abortion — then 3.7 mg prostaglandin F 2α would pass per hour from the amniotic fluid through the fetal membranes into the decidua.

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