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Ethinyl estradiol in peripheral plasma after oral administration of 30μg and 50μg to women

Authors
Journal
Contraception
0010-7824
Publisher
Elsevier
Publication Date
Volume
18
Issue
5
Identifiers
DOI: 10.1016/0010-7824(78)90031-8

Abstract

Abstract Plasma levels of ethinyl estradiol were measured by radioimmunoassay in five women after oral administration of 30μg and of 50μg of ethinyl estradiol. Peak levels of ethinyl estradiol were mostly observed within two hours after the tablet intake. The peak concentrations found were 50–90 pg and 95–135 pg for the two doses administered. Twenty-four hours after the administration of the tablets, the plasma concentration of ethinyl estradiol did not exceed the plasma blank values (25 pg/ml) in most women.

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