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Water absorption in experimental closed segment obstruction of the ileum in man

Authors
Publisher
Elsevier Inc.
Publication Date
Volume
121
Issue
1
Identifiers
DOI: 10.1016/0002-9610(71)90083-3

Abstract

Abstract The effect of increased intraluminal pressure on secretion and absorption from the human ileum was measured in volunteers with ileostomies. Absorption of a test solution was found to increase at moderate elevations of pressure, but fell below normal at pressures three or four times normal. Conversely, secretion of fluid into the lumen increased as pressure rose. These findings suggest that increased secretion is the primary cause of fluid loss and distention in closed loop intestinal obstruction, while decreased absorption plays a relatively less important role.

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