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The validation of biochemical assays by recovery data with special reference to serum iron

Authors
Journal
Clinica Chimica Acta
0009-8981
Publisher
Elsevier
Publication Date
Volume
33
Issue
1
Identifiers
DOI: 10.1016/0009-8981(71)90271-3
Disciplines
  • Biology
  • Chemistry
  • Medicine

Abstract

Abstract A procedure is described which may be used to validate biochemical analyses based on protein precipitation. It is divided into two stages in which the recovery of added substrate is estimated by isotopic and colorimetric analysis and compared with similar recovery from standards. It is sensitive and simple to perform, and provides information on the source and magnitude of procedural errors.

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