Abstract Consistence of topology for 3D models with such rich details as pores and wrinkles is very important for performing higher level tasks like deformation and animation. In this paper, we propose a novel wrinkle-aware registration method, which aligns not only the large-scale poses, but also high-resolution deformable details, in a unified framework. Using large-scale alignment enables us to solve a template-based energy minimization problem through pure Euclidean measurement. Fine-scale features are aligned by firstly computing crest lines for both the intermediately registered mesh and the target, and then evaluating the shape descriptors at the feature points, followed by a graph matching procedure to achieve a global optimization of the closest point matching. Experiments show that our method is effective and robust in preserving the quality of the source, while matching the fine-scale details of the target.