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Binding of human immunoglobulin M toStaphylococcus aureusbearing protein A

Authors
Journal
Immunology Letters
0165-2478
Publisher
Elsevier
Publication Date
Volume
4
Issue
6
Identifiers
DOI: 10.1016/0165-2478(82)90058-x
Disciplines
  • Biology

Abstract

Abstract Human immunoglobulin M binds to protein A-bearing Staphylococcus aureus. This binding is specific for protein A since it is inhibited by rabbit Fab against Staphylococcal protein A. Analysis of the IgM binding data gives an apparent K D of 0.94 nM and a maximum capacity of approximately 2 × 10 3 binding sites of IgM per bacteria.

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