Affordable Access

Publisher Website

Regulation of pre-mRNA splicing in metazoa

Authors
Publisher
Elsevier Ltd
Publication Date
Volume
7
Issue
2
Identifiers
DOI: 10.1016/s0959-437x(97)80130-x
Disciplines
  • Biology

Abstract

Abstract Recent studies have identified additional cis-acting sequence elements that can either positively or negatively regulate pre-mRNA splicing. Trans-acting protein factors involved in tissue-specific splicing regulation have been characterized. The functions of splicing factors have been explored in vivo and certain splicing factors have been demonstrated to be essential for proper development and cell viability. Kinases that can specifically phosphorylate splicing factors have been identified and phosphorylation has been shown to influence the activity of splicing factors, consistent with a role for phosphorylation in splicing regulation.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Regulation of pre-mRNA splicing in metazoa.

on Current Opinion in Genetics &... April 1997

Biochemistry and regulation of pre-mRNA splicing

on Current Opinion in Cell Biolog... Jan 01, 1996

Regulation of alternative pre-mRNA splicing.

on Briefings in functional genomi... October 2002
More articles like this..