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Hematological and biosynthetic features of β<sup>0</sup>-thalassemia with an associated α-thalassemia heterozygosity in Sardinia

Taylor & Francis
Publication Date
  • Bio/10 Biochimica
  • Med/15 Malattie Del Sangue


Total hemoglobin, PCV, hemoglobin A2 and hemoglobin F were determined in controls, β0-thal heterozygotes and α-thal+ β thal heterozygotes. Also the distribution of mean corpuscular volume and the mean corpuscular hemoglobin values in Sardinian β0-thal heterozygotes with and without an associated α-thal and the ratio of α/β chain synthesis in β0-thal heterozygotes with or without an associated α-thal were studied.

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