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Reversible cross-linking of cellular components of adherent fibroblasts to fibronectin and lectin-coated substrata

Authors
Journal
Experimental Cell Research
0014-4827
Publisher
Elsevier
Publication Date
Volume
134
Issue
2
Identifiers
DOI: 10.1016/0014-4827(81)90453-5
Disciplines
  • Biology

Abstract

Abstract Using matrix-immobilized proteins containing photo-labile cross-linking reagents we have been able to probe the underside of cells in the early stages of active spreading. Similar cellular components of hamster fibroblasts appear to be present in closest proximity to substrata containing fibronectin, ricin, concanavalin A (conA) or soybean agglutinin (SBA).

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