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Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants

Authors
Journal
Acta Crystallographica Section D Biological Crystallography
0907-4449
Publisher
International Union of Crystallography
Publication Date
Volume
67
Issue
6
Identifiers
DOI: 10.1107/s0907444911011541
Keywords
  • Research Papers

Abstract

Structural studies revealed a proline switch as a novel mechanism for the multidrug-resistant nature of multidrug-resistant clinical isolate 769 HIV-1 protease variants.

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