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[24-h dynamics of urination in patients with overactive urinary bladder].

Authors
Type
Published Article
Journal
Urologii︠a︡ (Moscow, Russia : 1999)
Publication Date
Issue
4
Identifiers
PMID: 17915449
Source
Medline

Abstract

Home 3-day uroflowmetry was made in 41 female patients (mean age 46 years) before and after therapy for overactive bladder (OB). The course of therapy lasting from 6 weeks to 3 months included M-cholinolytics and vascular medication. Estimation of the bladder capacity in different time of 24-h period revealed circadian deviations of urinary flow and volumes. Administration of short-term M-cholinolytics enables chronotherapy providing maximal effects within 4-6 hours, possibility to vary doses. In view of this, optimal cholinergic therapy of OB is trospium chloride which has necessary properties, high safety and wide dose range.

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