Abstract The aim of the present study is to predict marital satisfaction based on spiritual intelligence. The statistical population of the study consisted of all couples who referred to [family] counseling centers of Tehran in 2012. A sample of 240 individuals (120 women and 120 men) was selected from among this population in counseling centers of Tehran using random multistage sampling method. Additionally, stepwise multivariate regression was used to examine research hypotheses. The results indicated that, while relying on the inner core of spiritual intelligence, the element of spiritual life had the largest contribution to the prediction of the criterion variable and explained 35.2% of the marital satisfaction variance. Adding the element of “perception of and communication with the origins of the universe” to the equation increased the explanation coefficient to 37.1%. In addition, the results showed that the elements of spiritual intelligence among women and men explain marital satisfaction differently. Therefore, it is recommended that family therapists also consider the role of religious beliefs as an important factor in both the incidence of marital conflicts and solving them.