23-valent pneumococcal polysaccharide vaccine in HIV-1-infected Ugandan adults: double-blind, randomised and placebo controlled trial.
- Authors
- Type
- Published Article
- Journal
- The Lancet
- Publisher
- Elsevier BV
- Publication Date
- Jun 17, 2000
- Volume
- 355
- Issue
- 9221
- Pages
- 2106–2111
- Identifiers
- PMID: 10902624
- Source
- Medline
- Keywords
- License
- Unknown
Abstract
23-valent pneumococcal polysaccharide vaccination is ineffective in HIV-1-infected Ugandan adults and probably has little, or no, public health value elsewhere in sub-Saharan Africa. Increased rates of pneumococcal disease in vaccine recipients may necessitate a reappraisal of this intervention in other settings.