To examine the nature of daily hassles as perceived by African-American adolescen females. DESIGN AND METHODS . As part of a larger, cross-sectional study, nonrandom network sampling technique was used to survey 178 adolescent girls between the ages of 11 and 19. RESULTS . This study found that the most common hassles were school and academic, followed by family and economic hassles, peer and social hassles, and personal safety hassles. Socioeconomic factors were strongly associated with the level of hassles reported. PRACTICE IMPLICATIONS . Assess African-American girl's perception of daily hassles, specifically school- and family- related hassles, and also examine the interrelationship between the type of hassles and health problems.