Affordable Access

Publisher Website

μ-Opioid receptor binding in chicken brain in relation to degree of food restriction: a quantitative autoradiographic study

Authors
Journal
Brain Research
0006-8993
Publisher
Elsevier
Publication Date
Volume
742
Identifiers
DOI: 10.1016/s0006-8993(96)01088-8
Keywords
  • Opioid Binding
  • Quantitative Autoradiography
  • Chicken Brain
  • Food Restriction
Disciplines
  • Biology
  • Pharmacology

Abstract

Abstract Quantitative receptor autoradiography was used to measure differences in [ 3H]DAGO binding to μ-opioid receptors in selected fore-and midbrain regions of chickens subject to varying degrees of chronic food restriction: either R (a recommended restricted ration), 2R (twice recommended restricted ration) or AL (ad libitum). A significant increase in binding of 75% was observed in the paleostriatum primitivum (a homologue of the mammalian globus pallidus) with the R treatment compared to the 2R and AL treatments. This finding concurs with results of earlier pharmacological manipulations with opioid antagonists, which indicated that activation of μ-opioid receptors plays a contributory role in reinforcement of post-feeding oral stereotypies in chickens subject to the same R treatment.

There are no comments yet on this publication. Be the first to share your thoughts.